Version 5.4
Mus musculus Protein: Prune2
Summary
InnateDB Protein IDBP-150593.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prune2
Protein Name prune homolog 2 (Drosophila)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000084977
InnateDB Gene IDBG-150591 (Prune2)
Protein Structure
UniProt Annotation
Function May play an important role in regulating differentiation, survival and aggressiveness of the tumor cells. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0016462 pyrophosphatase activity
Biological Process
GO:0006915 apoptotic process
GO:0008152 metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
Protein Structure and Domains
PDB ID MGI:1925004
InterPro IPR001251 CRAL-TRIO domain
IPR004097 DHHA2
IPR022181 Bcl2-/adenovirus E1B 19kDa-interacting protein 2
PFAM PF00650
PF13716
PF02833
PF12496
PRINTS
PIRSF
SMART SM00516
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q52KR3
PhosphoSite PhosphoSite-Q52KR3
TrEMBL Q8CA96
UniProt Splice Variant
Entrez Gene 353211
UniGene Mm.489758
RefSeq NP_851993
MGI ID
MGI Symbol Prune2
OMIM
CCDS CCDS50400
HPRD
IMGT
EMBL AC126674 AC128703 AC147026 AK020727 AK038997 AK039241 AK054190 AK165582 AK170001 AK172939 BC094224 BC095978 FR693373 GQ403051
GenPept AAH94224 AAH95978 ADJ67999 BAB32192 BAC30198 BAC30291 BAC35688 BAD32217 BAE38273 BAE41506 CBX24839

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca