Version 5.4
Mus musculus Protein: Adamtsl2
Summary
InnateDB Protein IDBP-150640.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Adamtsl2
Protein Name ADAMTS-like 2
Synonyms A930008K15Rik; tcp-1;
Species Mus musculus
Ensembl Protein ENSMUSP00000088774
InnateDB Gene IDBG-150638 (Adamtsl2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0031012 extracellular matrix
Protein Structure and Domains
PDB ID MGI:1925044
InterPro IPR000884 Thrombospondin, type 1 repeat
IPR010294 ADAM-TS Spacer 1
IPR010909 PLAC
IPR013273 Peptidase M12B, ADAM-TS
PFAM PF00090
PF05986
PF08686
PRINTS PR01857
PIRSF
SMART SM00209
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7TSK7
PhosphoSite PhosphoSite-Q7TSK7
TrEMBL A1A5B7
UniProt Splice Variant
Entrez Gene 77794
UniGene Mm.330088
RefSeq NP_084257
MGI ID
MGI Symbol Adamtsl2
OMIM
CCDS CCDS15824
HPRD
IMGT
EMBL AB096928 AK156991 BC128568 BC129984
GenPept AAI28569 AAI29985 BAC76875 BAE33926

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca