Version 5.4
Mus musculus Protein: Plekhg3
Summary
InnateDB Protein IDBP-150720.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Plekhg3
Protein Name pleckstrin homology domain containing, family G (with RhoGef domain) member 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000074729
InnateDB Gene IDBG-150716 (Plekhg3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005089 Rho guanyl-nucleotide exchange factor activity
Biological Process
GO:0008150 biological_process
GO:0032319 regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:2388284
InterPro IPR000219 Dbl homology (DH) domain
IPR001849 Pleckstrin homology domain
PFAM PF00621
PF00169
PRINTS
PIRSF
SMART SM00325
SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q4VAC9
PhosphoSite PhosphoSite-Q4VAC9
TrEMBL
UniProt Splice Variant
Entrez Gene 263406
UniGene Mm.420834
RefSeq NP_722499
MGI ID
MGI Symbol Plekhg3
OMIM
CCDS CCDS25994
HPRD
IMGT
EMBL AC163033 AK080928 AK162025 AK172977 BC030417 BC031136 BC049264 BC096443
GenPept AAH30417 AAH31136 AAH49264 AAH96443 BAC38083 BAD32255 BAE36687

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca