InnateDB Protein
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IDBP-150746.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Plb1
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Protein Name
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phospholipase B1
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000098928
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InnateDB Gene
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IDBG-150740 (Plb1)
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Protein Structure
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Function |
Membrane-associated phospholipase. Exhibits a calcium- independent broad substrate specificity including phospholipase A2/lysophospholipase activity. Preferential hydrolysis at the sn-2 position of diacylphospholipids and diacyglycerol, whereas it shows no positional specificity toward triacylglycerol. Exhibits also esterase activity toward p-nitrophenyl. May act on the brush border membrane to facilitate the absorption of digested lipids (By similarity). {ECO:0000250}.
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Subcellular Localization |
Apical cell membrane {ECO:0000250}; Single- pass type I membrane protein {ECO:0000250}. Note=Present in the intestinal brush border membranes. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1922406
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InterPro |
IPR001087
Lipase, GDSL
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PFAM |
PF00657
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q3TTY0
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PhosphoSite |
PhosphoSite-Q3TTY0
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TrEMBL |
Q8K255
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UniProt Splice Variant |
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Entrez Gene |
665270
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UniGene |
Mm.160067
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RefSeq |
NP_084348
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MGI ID |
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MGI Symbol |
Plb1
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OMIM |
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CCDS |
CCDS39060
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HPRD |
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IMGT |
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EMBL |
AC102372
AC111030
AK015993
AK161095
BC033606
BC119077
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GenPept |
AAH33606
AAI19078
BAB30072
BAE36193
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