Version 5.4
Mus musculus Protein: Panx3
Summary
InnateDB Protein IDBP-150887.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Panx3
Protein Name pannexin 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000011262
InnateDB Gene IDBG-150885 (Panx3)
Protein Structure
UniProt Annotation
Function Structural component of the gap junctions and the hemichannels.
Subcellular Localization Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255PROSITE-ProRule:PRU00351}. Cell junction, gap junction.
Disease Associations
Tissue Specificity Expressed in skin, cartilage, heart, lung, liver, spleen, thymus and kidney. Not expressed in brain.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0055077 gap junction hemi-channel activity
Biological Process
GO:0006811 ion transport
GO:0007267 cell-cell signaling
GO:0034214 protein hexamerization
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005921 gap junction
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1918881
InterPro IPR000990 Innexin
PFAM PF00876
PRINTS PR01262
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CEG0
PhosphoSite PhosphoSite-Q8CEG0
TrEMBL Q6IMP0
UniProt Splice Variant
Entrez Gene 208098
UniGene Mm.413261
RefSeq NP_766042
MGI ID
MGI Symbol Panx3
OMIM
CCDS CCDS22984
HPRD
IMGT
EMBL AK028288 AK036933 BC052822 BK000662 CH466522
GenPept AAH52822 BAC25860 BAC29644 DAA00383 EDL25441

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca