InnateDB Protein
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IDBP-151395.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Fntb
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Protein Name
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farnesyltransferase, CAAX box, beta
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Synonyms
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2010013E13Rik; AA409500;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000035498
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InnateDB Gene
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IDBG-151393 (Fntb)
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Protein Structure
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Function |
Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C- terminus of several proteins having the C-terminal sequence Cys- aliphatic-aliphatic-X. {ECO:0000269PubMed:21520375}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1861305
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InterPro |
IPR001330
Prenyltransferase/squalene oxidase
IPR008930
Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
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PFAM |
PF00432
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8K2I1
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PhosphoSite |
PhosphoSite-Q8K2I1
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
110606
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UniGene |
Mm.151174
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RefSeq |
NP_666039
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MGI ID |
3PZ4
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MGI Symbol |
Fntb
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OMIM |
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CCDS |
CCDS25998
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HPRD |
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IMGT |
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EMBL |
BC031417
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GenPept |
AAH31417
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