Version 5.4
Mus musculus Protein: Tspan14
Summary
InnateDB Protein IDBP-151415.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tspan14
Protein Name tetraspanin 14
Synonyms AA958793; D14Ertd226e; Tm4sf14;
Species Mus musculus
Ensembl Protein ENSMUSP00000035263
InnateDB Gene IDBG-151413 (Tspan14)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0019899 enzyme binding
Biological Process
GO:0045747 positive regulation of Notch signaling pathway
GO:0051604 protein maturation
GO:0090002 establishment of protein localization to plasma membrane
Cellular Component
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0097197 tetraspanin-enriched microdomain
Protein Structure and Domains
PDB ID MGI:1196325
InterPro IPR000301 Tetraspanin
IPR008952 Tetraspanin, EC2 domain
IPR018499 Tetraspanin/Peripherin
PFAM PF00335
PRINTS PR00259
PIRSF PIRSF002419
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8QZY6
PhosphoSite PhosphoSite-Q8QZY6
TrEMBL
UniProt Splice Variant
Entrez Gene 52588
UniGene Mm.473080
RefSeq NP_666040
MGI ID
MGI Symbol Tspan14
OMIM
CCDS CCDS26956
HPRD
IMGT
EMBL AK030593 BC024611 BC025568 BC026574
GenPept AAH24611 AAH25568 AAH26574 BAC27035

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca