InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Adam26a

Summary

InnateDB Protein

IDBP-151570.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Adam26a

Protein Name

a disintegrin and metallopeptidase domain 26A (testase 3)

Synonyms

Adam26; Dtgn4;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000058256

InnateDB Gene

IDBG-151568 (Adam26a)

Protein Structure

UniProt Annotation

Function

Sperm surface membrane protein that may be involved in spermatogenesis and fertilization.

Subcellular Localization

Membrane; Single-pass type I membrane protein.

Disease Associations

Tissue Specificity

Expressed specifically in testis.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004222	metalloendopeptidase activity
GO:0005178	integrin binding
GO:0008237	metallopeptidase activity
GO:0008270	zinc ion binding

Biological Process

GO:0006508	proteolysis
GO:0007275	multicellular organismal development
GO:0007283	spermatogenesis
GO:0030154	cell differentiation

Cellular Component

GO:0005575	cellular_component
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:105985

InterPro

IPR001590 Peptidase M12B, ADAM/reprolysin
IPR001762 Blood coagulation inhibitor, Disintegrin
IPR002870 Peptidase M12B, propeptide
IPR006586 ADAM, cysteine-rich

PFAM

PF01421
PF00200
PF01562
PF08516

PRINTS

PR00289

PIRSF

SMART

SM00050
SM00608

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt