Version 5.4
Homo sapiens Protein: MIPEP
Summary
InnateDB Protein IDBP-15181.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MIPEP
Protein Name mitochondrial intermediate peptidase
Synonyms HMIP; MIP;
Species Homo sapiens
Ensembl Protein ENSP00000371607
InnateDB Gene IDBG-15179 (MIPEP)
Protein Structure
UniProt Annotation
Function Cleaves proteins, imported into the mitochondrion, to their mature size.
Subcellular Localization Mitochondrion matrix.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 8 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0006627 protein processing involved in protein targeting to mitochondrion
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
Protein Structure and Domains
PDB ID
InterPro IPR001567 Peptidase M3A/M3B
PFAM PF01432
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99797
PhosphoSite PhosphoSite-Q99797
TrEMBL
UniProt Splice Variant
Entrez Gene 4285
UniGene Hs.507498
RefSeq NP_005923
HUGO HGNC:7104
OMIM 602241
CCDS CCDS9303
HPRD 03761
IMGT
EMBL AK291923 AL139080 AL157368 AL445985 BC009934 U80034
GenPept AAC51231 AAH09934 BAF84612 CAI15091 CAI39630 CAM20040

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca