InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cpn2

Summary

InnateDB Protein

IDBP-151932.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cpn2

Protein Name

carboxypeptidase N, polypeptide 2

Synonyms

1300018K11Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000069318

InnateDB Gene

IDBG-151930 (Cpn2)

Protein Structure

UniProt Annotation

Function

The 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation. Under some circumstances it may be an allosteric modifier of the catalytic subunit (By similarity). {ECO:0000250}.

Subcellular Localization

Secreted {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0005576	extracellular region
GO:0070062	extracellular vesicular exosome
GO:0072562	blood microparticle

Protein Structure and Domains

PDB ID

MGI:1919006

InterPro

IPR000372 Leucine-rich repeat-containing N-terminal
IPR000483 Cysteine-rich flanking region, C-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype

PFAM

PF01462
PF01463
PF00560
PF13504
PF13855

PRINTS

PIRSF

SMART

SM00013
SM00082
SM00369

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9DBB9