Version 5.4
Mus musculus Protein: Aldh1a7
Summary
InnateDB Protein IDBP-152001.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Aldh1a7
Protein Name aldehyde dehydrogenase family 1, subfamily A7
Synonyms Ahd2-like; AI987940; Aldh-pb; Aldh1a4; Aldhpb;
Species Mus musculus
Ensembl Protein ENSMUSP00000025656
InnateDB Gene IDBG-151999 (Aldh1a7)
Protein Structure
UniProt Annotation
Function Can oxidize benzaldehyde, propionaldehyde and acetaldehyde (By similarity). No detectable activity with retinal. {ECO:0000250, ECO:0000269PubMed:10191271}.
Subcellular Localization Cytoplasm {ECO:0000250UniProtKB:P13601}.
Disease Associations
Tissue Specificity Highest level in liver, high level in lung, low level in kidney and testis. {ECO:0000269PubMed:10191271}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003995 acyl-CoA dehydrogenase activity
GO:0004029 aldehyde dehydrogenase (NAD) activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006068 ethanol catabolic process
GO:0008152 metabolic process
GO:0008218 bioluminescence
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1347050
InterPro IPR008670 Acyl-CoA reductase, LuxC
IPR015590 Aldehyde dehydrogenase domain
IPR016161 Aldehyde/histidinol dehydrogenase
PFAM PF05893
PF00171
PRINTS
PIRSF PIRSF009414
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O35945
PhosphoSite PhosphoSite-O35945
TrEMBL B2RTL5
UniProt Splice Variant
Entrez Gene 26358
UniGene Mm.14609
RefSeq NP_036051
MGI ID
MGI Symbol Aldh1a7
OMIM
CCDS CCDS29696
HPRD
IMGT
EMBL BC046315 BC139412 BC139413 CH466534 U96401
GenPept AAB64411 AAH46315 AAI39413 AAI39414 EDL41578

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca