Version 5.4
Mus musculus Protein: Slitrk3
Summary
InnateDB Protein IDBP-152004.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slitrk3
Protein Name SLIT and NTRK-like family, member 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000088561
InnateDB Gene IDBG-152002 (Slitrk3)
Protein Structure
UniProt Annotation
Function Suppresses neurite outgrowth. {ECO:0000269PubMed:14550773}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Broadly expressed in embryonic brain with highest expression in cortical plate, pyramidal cell layer of the hippocampus, thalamus and hypothalamus. {ECO:0000269PubMed:14550773}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0007409 axonogenesis
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2679447
InterPro IPR000483 Cysteine-rich flanking region, C-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
PFAM PF01463
PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00082
SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q810B9
PhosphoSite PhosphoSite-Q810B9
TrEMBL Q3UTG8
UniProt Splice Variant
Entrez Gene 386750
UniGene Mm.397935
RefSeq NP_942564
MGI ID
MGI Symbol Slitrk3
OMIM
CCDS CCDS17410
HPRD
IMGT
EMBL AB097572 AK139438 AK158856 BC066059 CH466547
GenPept AAH66059 BAC67206 BAE24012 BAE34696 EDL15486

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca