InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Il17b

Summary

InnateDB Protein

IDBP-152142.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Il17b

Protein Name

interleukin 17B

Synonyms

1110006O16Rik; 1700006N07Rik; Zcyto7;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000025471

InnateDB Gene

IDBG-152140 (Il17b)

Protein Structure

UniProt Annotation

Function

Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1. {ECO:0000250}.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005125	cytokine activity

Biological Process

GO:0006954	inflammatory response
GO:0030593	neutrophil chemotaxis
GO:1900017	positive regulation of cytokine production involved in inflammatory response

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space

Protein Structure and Domains

PDB ID

MGI:1928397

InterPro

IPR010345 Interleukin-17 family
IPR020440 Interleukin-17, chordata
IPR029034 Cystine-knot cytokine

PFAM

PF06083

PRINTS

PR01932

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9QXT6

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

56069

UniGene

Mm.59313

RefSeq

NP_062381

MGI ID

MGI Symbol

Il17b

OMIM

CCDS

CCDS29286

HPRD

IMGT

EMBL

AF184970 AF218726 AF250308 AK003506 BC002271

GenPept

AAF01319 AAG44135 AAH02271 AAK37427