InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tomm40

Summary

InnateDB Protein

IDBP-152168.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tomm40

Protein Name

translocase of outer mitochondrial membrane 40 homolog (yeast)

Synonyms

AW539759; Mom35; Tom40;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000032555

InnateDB Gene

IDBG-152166 (Tomm40)

Protein Structure

UniProt Annotation

Function

Channel-forming protein essential for import of protein precursors into mitochondria. {ECO:0000250}.

Subcellular Localization

Mitochondrion outer membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 41 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	41 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0015288	porin activity

Biological Process

GO:0006626	protein targeting to mitochondrion
GO:0006811	ion transport
GO:0055085	transmembrane transport

Cellular Component

GO:0005739	mitochondrion
GO:0005741	mitochondrial outer membrane
GO:0005742	mitochondrial outer membrane translocase complex
GO:0016021	integral component of membrane
GO:0032592	integral component of mitochondrial membrane
GO:0046930	pore complex
GO:0070062	extracellular vesicular exosome