Version 5.4
Mus musculus Protein: Spred2
Summary
InnateDB Protein IDBP-152430.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Spred2
Protein Name sprouty-related, EVH1 domain containing 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000090988
InnateDB Gene IDBG-152428 (Spred2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005173 stem cell factor receptor binding
GO:0005515 protein binding
GO:0019901 protein kinase binding
Biological Process
GO:0000188 inactivation of MAPK activity
GO:0007275 multicellular organismal development
GO:0009966 regulation of signal transduction
GO:0010801 negative regulation of peptidyl-threonine phosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0031410 cytoplasmic vesicle
Protein Structure and Domains
PDB ID MGI:2150019
InterPro IPR000697 WH1/EVH1
IPR007875 Sprouty
PFAM PF00568
PF05210
PRINTS
PIRSF
SMART SM00461
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5SRF8
UniProt Splice Variant
Entrez Gene 114716
UniGene Mm.413985
RefSeq XP_006514520
MGI ID
MGI Symbol Spred2
OMIM
CCDS
HPRD
IMGT
EMBL AL645609 AL672084
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca