Version 5.4
| Mus musculus Protein: Ear2 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-152531.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Ear2 | ||||||||
| Protein Name | eosinophil-associated, ribonuclease A family, member 2 | ||||||||
| Synonyms | 2; EAR-13; EAR-2; ECP; ECP 2; mR3; Raf3; Rnase2; Rnase3; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000074386 | ||||||||
| InnateDB Gene | IDBG-152529 (Ear2) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Cytotoxin and helminthotoxin with ribonuclease activity. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities. | ||||||||
| Subcellular Localization | Cytoplasmic granule {ECO:0000250}. Note=Matrix of eosinophil's large specific granule. {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:108020 | ||||||||
| InterPro |
IPR001427
Ribonuclease A IPR023412 Ribonuclease A-domain |
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| PFAM |
PF00074
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| PRINTS |
PR00794
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| PIRSF | |||||||||
| SMART |
SM00092
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | P97425 | ||||||||
| PhosphoSite | PhosphoSite-NP_001012784 | ||||||||
| TrEMBL | W0UVF7 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 53876 | ||||||||
| UniGene | Mm.484825 | ||||||||
| RefSeq | NP_059084 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Ear2 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS26968 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AF306664 AF306665 BC065391 BC094626 CH466668 HG328947 U72031 | ||||||||
| GenPept | AAB37785 AAG25991 AAG25992 AAH65391 AAH94626 CDG32023 EDL33999 | ||||||||