Version 5.4
Mus musculus Protein: Smpdl3a
Summary
InnateDB Protein IDBP-152660.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Smpdl3a
Protein Name sphingomyelin phosphodiesterase, acid-like 3A
Synonyms 0610010C24Rik; AI529588; ASM3A; ASML3; ASML3A;
Species Mus musculus
Ensembl Protein ENSMUSP00000020022
InnateDB Gene IDBG-152658 (Smpdl3a)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004767 sphingomyelin phosphodiesterase activity
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0006685 sphingomyelin catabolic process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID MGI:1931437
InterPro IPR004843 Calcineurin-like phosphoesterase domain, apaH type
IPR017064 Acid sphingomyelinase-like phosphodiesterase, predicted
IPR029052 Metallo-dependent phosphatase-like
PFAM PF00149
PRINTS
PIRSF PIRSF036767
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P70158
PhosphoSite PhosphoSite-P70158
TrEMBL
UniProt Splice Variant
Entrez Gene 57319
UniGene Mm.2379
RefSeq NP_065586
MGI ID
MGI Symbol Smpdl3a
OMIM
CCDS CCDS23857
HPRD
IMGT
EMBL AK151683 AK152282 BC139288 BC139289 CH466540 Y08135
GenPept AAI39289 AAI39290 BAE30607 BAE31096 CAA69329 EDL05124

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca