Version 5.4
Mus musculus Protein: Nrbp2
Summary
InnateDB Protein IDBP-152733.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nrbp2
Protein Name nuclear receptor binding protein 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000019516
InnateDB Gene IDBG-152731 (Nrbp2)
Protein Structure
UniProt Annotation
Function May regulate apoptosis of neural progenitor cells during their differentiation. {ECO:0000269PubMed:18619852}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:18619852}.
Disease Associations
Tissue Specificity Expressed in Purkinje cells of the cerebellum and neurons in the CA3 region of the hippocampus. Also detected in non-neural tissues including mesenchymal layer adjacent to epithelium in developing bronchi of the lung, the epithelium of the stomach as well as cells in the liver. {ECO:0000269PubMed:18619852}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0016242 negative regulation of macroautophagy
GO:0030182 neuron differentiation
GO:0043524 negative regulation of neuron apoptotic process
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:2385017
InterPro IPR011009 Protein kinase-like domain
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91V36
PhosphoSite PhosphoSite-Q91V36
TrEMBL
UniProt Splice Variant
Entrez Gene 223649
UniGene Mm.101946
RefSeq NP_659096
MGI ID
MGI Symbol Nrbp2
OMIM
CCDS CCDS27561
HPRD
IMGT
EMBL AC116487 BC011468 BC012437 BC025042
GenPept AAH11468 AAH12437 AAH25042

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca