Version 5.4
Mus musculus Protein: Haus7
Summary
InnateDB Protein IDBP-152744.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Haus7
Protein Name HAUS augmin-like complex, subunit 7
Synonyms 1110020L19Rik; Uchl5ip; Uip1;
Species Mus musculus
Ensembl Protein ENSMUSP00000076479
InnateDB Gene IDBG-152740 (Haus7)
Protein Structure
UniProt Annotation
Function Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Note=Localizes to interphase centrosomes and to mitotic spindle microtubules. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0031996 thioesterase binding
Biological Process
GO:0007067 mitotic nuclear division
GO:0051225 spindle assembly
GO:0051297 centrosome organization
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005819 spindle
GO:0005874 microtubule
GO:0005886 plasma membrane
GO:0070652 HAUS complex
Protein Structure and Domains
PDB ID MGI:1920988
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BKT8
PhosphoSite PhosphoSite-Q8BKT8
TrEMBL
UniProt Splice Variant
Entrez Gene 73738
UniGene Mm.264899
RefSeq NP_996987
MGI ID
MGI Symbol Haus7
OMIM
CCDS CCDS30203
HPRD
IMGT
EMBL AK050729 AL732461 AY029337 BC025464 CH466650
GenPept AAH25464 AAK38738 BAC34395 CAM27431 CAM27432 EDL29899

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca