InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Auh

Summary

InnateDB Protein

IDBP-152825.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Auh

Protein Name

AU RNA binding protein/enoyl-coenzyme A hydratase

Synonyms

C77140; W91705;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000021913

InnateDB Gene

IDBG-152823 (Auh)

Protein Structure

UniProt Annotation

Function

Catalyzes the conversion of 3-methylglutaconyl-CoA to 3- hydroxy-3-methylglutaryl-CoA. Has very low enoyl-CoA hydratase activity. Was originally identified as RNA-binding protein that binds in vitro to clustered 5'-AUUUA-3' motifs (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion {ECO:0000269PubMed:10072761}.

Disease Associations

Tissue Specificity

Detected in heart, brain, liver, spleen, skeletal muscle and kidney. {ECO:0000269PubMed:10072761}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003730	mRNA 3'-UTR binding
GO:0003824	catalytic activity
GO:0004300	enoyl-CoA hydratase activity
GO:0004490	methylglutaconyl-CoA hydratase activity