Version 5.4
| Mus musculus Protein: Zfyve26 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-152947.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Zfyve26 | ||||||||
| Protein Name | zinc finger, FYVE domain containing 26 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000021547 | ||||||||
| InnateDB Gene | IDBG-152945 (Zfyve26) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Phosphatidylinositol 3-phosphate-binding protein required for the abcission step in cytokinesis: recruited to the midbody during cytokinesis and acts as a regulator of abcission. May also be required for efficient homologous recombination DNA double-strand break repair (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Midbody {ECO:0000250}. Note=Localizes to the centrosome during all stages of the cell cycle. Recruited to the midbody during cytokinesis by KIF13A (By similarity). {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1924767 | ||||||||
| InterPro |
IPR000306
FYVE zinc finger IPR009061 DNA binding domain, putative IPR011011 Zinc finger, FYVE/PHD-type IPR017455 Zinc finger, FYVE-related |
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| PFAM |
PF01363
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00064
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q5DU37 | ||||||||
| PhosphoSite | PhosphoSite-Q5DU37 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 211978 | ||||||||
| UniGene | Mm.297919 | ||||||||
| RefSeq | NP_001008550 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Zfyve26 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS36481 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK029679 AK041668 AK132344 AK169541 AK220333 BC006654 BC141359 | ||||||||
| GenPept | AAH06654 AAI41360 BAC26561 BAC31027 BAD90401 BAE21117 BAE41219 | ||||||||