InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tmem129

Summary

InnateDB Protein

IDBP-153417.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tmem129

Protein Name

transmembrane protein 129

Synonyms

0610039G24Rik; 2410015J15Rik; AA409575;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000019439

InnateDB Gene

IDBG-153415 (Tmem129)

Protein Structure

UniProt Annotation

Function

E3 ubiquitin-protein ligase involved in ER-associated protein degradation, preferentially associates with the E2 enzyme UBE2J2. Exploited by viral US11 proteins to mediate HLA class I proteins degradation (By similarity). {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0005575	cellular_component
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1915616

InterPro

IPR018801 Putative transmembrane protein precursor

PFAM

PF10272

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8K304

PhosphoSite

PhosphoSite-Q8K304

TrEMBL

UniProt Splice Variant

Entrez Gene

68366

UniGene

Mm.332317

RefSeq

NP_080974

MGI ID

MGI Symbol

Tmem129

OMIM

CCDS

CCDS19206

HPRD

IMGT

EMBL

AK002836 AK172044 BC029088 BC094042

GenPept

AAH29088 AAH94042 BAB22394 BAE42795