Version 5.4
Mus musculus Protein: St8sia3
Summary
InnateDB Protein IDBP-153717.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol St8sia3
Protein Name ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
Synonyms AI847333; Siat8c; ST8SiaIII;
Species Mus musculus
Ensembl Protein ENSMUSP00000025477
InnateDB Gene IDBG-153715 (St8sia3)
Protein Structure
UniProt Annotation
Function May transfer sialic acid through alpha-2,8-linkages to alpha-2,3-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids.
Subcellular Localization Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in brain and testes.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity
GO:0008373 sialyltransferase activity
Biological Process
GO:0001574 ganglioside biosynthetic process
GO:0006486 protein glycosylation
GO:0006491 N-glycan processing
GO:0009100 glycoprotein metabolic process
GO:0009311 oligosaccharide metabolic process
GO:0097503 sialylation
Cellular Component
GO:0030173 integral component of Golgi membrane
Protein Structure and Domains
PDB ID MGI:106019
InterPro IPR001675 Glycosyl transferase, family 29
IPR012163 Sialyltransferase
PFAM PF00777
PRINTS
PIRSF PIRSF005557
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q64689
PhosphoSite PhosphoSite-
TrEMBL Q9CUJ6
UniProt Splice Variant
Entrez Gene 20451
UniGene Mm.252110
RefSeq NP_033208
MGI ID
MGI Symbol St8sia3
OMIM
CCDS CCDS29301
HPRD
IMGT
EMBL AK015874 AK133780 AK134678 BC075645 CH466528 X80502
GenPept AAH75645 BAB30012 BAE21835 BAE22237 CAA56665 EDL09712

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca