InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nlrp4e

Summary

InnateDB Protein

IDBP-153758.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nlrp4e

Protein Name

NLR family, pyrin domain containing 4E

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000075794

InnateDB Gene

IDBG-153756 (Nlrp4e)

Protein Structure

UniProt Annotation

Function

May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005524	ATP binding

Biological Process

GO:0006954	inflammatory response
GO:0008150	biological_process

Cellular Component

GO:0005575

cellular_component

Protein Structure and Domains

PDB ID

MGI:3056600

InterPro

IPR003590 Leucine-rich repeat, ribonuclease inhibitor subtype
IPR004020 DAPIN domain
IPR007111 NACHT nucleoside triphosphatase
IPR011029 Death-like domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF02758

PRINTS

PIRSF

SMART

SM00368

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q66X19