Version 5.4
| Mus musculus Protein: Samd4 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-153992.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Samd4 | ||||||||
| Protein Name | sterile alpha motif domain containing 4 | ||||||||
| Synonyms | 1700024G08Rik; 1700111L17Rik; 4933436G17Rik; Samd4a; Smaug; Smaug1; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000022386 | ||||||||
| InnateDB Gene | IDBG-153990 (Samd4) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Acts as a translational repressor of SRE-containing messengers. {ECO:0000250}. | ||||||||
| Subcellular Localization | Cytoplasm {ECO:0000269PubMed:16221671}. Cell projection, dendrite {ECO:0000269PubMed:16221671}. Cell junction, synapse, synaptosome {ECO:0000269PubMed:16221671}. Note=Colocalizes throughout the cytoplasm in granules with polyadenylated RNAs, PABPC1 and STAU1. Also frequently colocalizes in cytoplasmic stress granule-like foci with ELAVL1, TIA1 and TIAL1. Shuttles between the nucleus and the cytoplasm in a CRM1- dependent manner (By similarity). Enriched in synaptoneurosomes. {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Expressed in brain (at protein level). {ECO:0000269PubMed:16221671}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1921730 | ||||||||
| InterPro |
IPR001660
Sterile alpha motif domain IPR011510 Sterile alpha motif, type 2 IPR013761 Sterile alpha motif/pointed domain IPR021129 Sterile alpha motif, type 1 |
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| PFAM |
PF07647
PF00536 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00454
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8CBY1 | ||||||||
| PhosphoSite | PhosphoSite-Q8CBY1 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 74480 | ||||||||
| UniGene | Mm.397141 | ||||||||
| RefSeq | NP_001032298 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Samd4 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS26982 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AC131586 AC159006 AK017081 AK034323 AK134243 AK161277 AK163751 BC049740 BC145827 BC145829 CH466605 DQ278487 | ||||||||
| GenPept | AAH49740 AAI45828 AAI45830 ABB83932 BAB30585 BAC28674 BAE22061 BAE36288 BAE37479 EDL20734 | ||||||||