InnateDB Protein
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IDBP-1540.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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KRTAP22-1
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Protein Name
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keratin associated protein 22-1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000333887
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InnateDB Gene
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IDBG-1538 (KRTAP22-1)
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Protein Structure
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Function |
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR021743
Keratin-associated protein, type6/8/16/19/20
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PFAM |
PF11759
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q3MIV0
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
337979
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UniGene |
Hs.553700
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RefSeq |
NP_853651
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HUGO |
HGNC:18947
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OMIM |
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CCDS |
CCDS13601
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HPRD |
11216
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IMGT |
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EMBL |
AB096953
AP001069
BC101682
BC101686
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GenPept |
AAI01683
AAI01687
BAE46368
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