InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: L1cam

Summary

InnateDB Protein

IDBP-154018.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

L1cam

Protein Name

L1 cell adhesion molecule

Synonyms

CD171; L1; N-CAM-L1; NCAM-L1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000068135

InnateDB Gene

IDBG-154012 (L1cam)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005178	integrin binding
GO:0005515	protein binding
GO:0033691	sialic acid binding
GO:0042802	identical protein binding
GO:0043621	protein self-association

Biological Process

GO:0007156	homophilic cell adhesion
GO:0007157	heterophilic cell-cell adhesion
GO:0007159	leukocyte cell-cell adhesion
GO:0007166	cell surface receptor signaling pathway
GO:0007411	axon guidance
GO:0022409	positive regulation of cell-cell adhesion
GO:0031175	neuron projection development
GO:0033631	cell-cell adhesion mediated by integrin
GO:0034109	homotypic cell-cell adhesion
GO:0050850	positive regulation of calcium-mediated signaling

Cellular Component

GO:0009897	external side of plasma membrane
GO:0009986	cell surface
GO:0016020	membrane
GO:0042734	presynaptic membrane
GO:0043195	terminal bouton

Protein Structure and Domains

PDB ID

MGI:96721

InterPro

IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin

PFAM

PF00041
PF01108
PF07679
PF07686
PF00047

PRINTS

PIRSF

SMART

SM00408
SM00409
SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite