Version 5.4
Mus musculus Protein: Ormdl1
Summary
InnateDB Protein IDBP-154059.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ormdl1
Protein Name ORM1-like 1 (S. cerevisiae)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000027266
InnateDB Gene IDBG-154057 (Ormdl1)
Protein Structure
UniProt Annotation
Function Negative regulator of sphingolipid synthesis. {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006672 ceramide metabolic process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2181669
InterPro IPR007203 ORMDL
PFAM PF04061
PRINTS
PIRSF PIRSF018147
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q921I0
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 227102
UniGene Mm.489858
RefSeq NP_663492
MGI ID
MGI Symbol Ormdl1
OMIM
CCDS CCDS14952
HPRD
IMGT
EMBL AK050385 AK077562 BC012315 BC023695 BC025572
GenPept AAH12315 AAH23695 AAH25572 BAC34226 BAC36865

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca