Version 5.4
Mus musculus Protein: Coq4
Summary
InnateDB Protein IDBP-154450.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Coq4
Protein Name coenzyme Q4 homolog (yeast)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000028137
InnateDB Gene IDBG-154448 (Coq4)
Protein Structure
UniProt Annotation
Function Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides. {ECO:0000255HAMAP- Rule:MF_03111}.
Subcellular Localization Mitochondrion inner membrane {ECO:0000255HAMAP-Rule:MF_03111}; Peripheral membrane protein {ECO:0000255HAMAP-Rule:MF_03111}; Matrix side {ECO:0000255HAMAP- Rule:MF_03111}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006744 ubiquinone biosynthetic process
GO:0008150 biological_process
Cellular Component
GO:0005739 mitochondrion
GO:0031314 extrinsic component of mitochondrial inner membrane
Protein Structure and Domains
PDB ID MGI:1098826
InterPro IPR007715 Ubiquinone biosynthesis protein Coq4
PFAM PF05019
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BGB8
PhosphoSite PhosphoSite-Q8BGB8
TrEMBL Q8BLS2
UniProt Splice Variant
Entrez Gene 227683
UniGene Mm.245948
RefSeq NP_848808
MGI ID
MGI Symbol Coq4
OMIM
CCDS CCDS15857
HPRD
IMGT
EMBL AK039422 AK039676 AK043574 AK050459 AL845323 BC139373 BC139376 CH466542
GenPept AAI39374 AAI39377 BAC30344 BAC30416 BAC31585 BAC34269 CAM20267 EDL08421

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca