InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Npy2r

Summary

InnateDB Protein

IDBP-154456.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Npy2r

Protein Name

neuropeptide Y receptor Y2

Synonyms

NPY2-R;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000029633

InnateDB Gene

IDBG-154454 (Npy2r)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001601	peptide YY receptor activity
GO:0004930	G-protein coupled receptor activity
GO:0004983	neuropeptide Y receptor activity
GO:0005515	protein binding

Biological Process

GO:0001662	behavioral fear response
GO:0002793	positive regulation of peptide secretion
GO:0003151	outflow tract morphogenesis
GO:0003214	cardiac left ventricle morphogenesis
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007204	positive regulation of cytosolic calcium ion concentration
GO:0007218	neuropeptide signaling pathway
GO:0007263	nitric oxide mediated signal transduction
GO:0030818	negative regulation of cAMP biosynthetic process
GO:0031645	negative regulation of neurological system process
GO:0033603	positive regulation of dopamine secretion
GO:0045785	positive regulation of cell adhesion
GO:0045987	positive regulation of smooth muscle contraction
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep
GO:0046903	secretion
GO:0050805	negative regulation of synaptic transmission
GO:0051048	negative regulation of secretion
GO:0051930	regulation of sensory perception of pain
GO:0051967	negative regulation of synaptic transmission, glutamatergic
GO:0090394	negative regulation of excitatory postsynaptic membrane potential
GO:2000252	negative regulation of feeding behavior

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:108418

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000611 Neuropeptide Y receptor family
IPR001358 Neuropeptide Y2 receptor
IPR005395 Neuropeptide FF receptor family
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx

PFAM

PF00001
PF10320

PRINTS

PR00237
PR01012
PR01014
PR01570

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P97295