Version 5.4
| Mus musculus Protein: Adam21 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-154495.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Adam21 | ||||||||
| Protein Name | a disintegrin and metallopeptidase domain 21 | ||||||||
| Synonyms | Adam31; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000008582 | ||||||||
| InnateDB Gene | IDBG-154493 (Adam21) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | May be involved in sperm maturation and/or fertilization. May also be involved in epithelia functions associated with establishing and maintaining gradients of ions or nutrients. | ||||||||
| Subcellular Localization | Membrane; Single-pass type I membrane protein. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Highly expressed in Leydig cells. Expressed also in cauda epididymidis, vas deferens, convoluted tubules, kidney and the parietal cells of stomach. Not detected on developing spermatocytes or mature sperm. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1861229 | ||||||||
| InterPro |
IPR000742
Epidermal growth factor-like domain IPR001590 Peptidase M12B, ADAM/reprolysin IPR001762 Blood coagulation inhibitor, Disintegrin IPR002870 Peptidase M12B, propeptide IPR006586 ADAM, cysteine-rich |
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| PFAM |
PF00008
PF01421 PF00200 PF01562 PF08516 |
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| PRINTS |
PR00289
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| PIRSF | |||||||||
| SMART |
SM00181
SM00050 SM00608 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9JI76 | ||||||||
| PhosphoSite | PhosphoSite-Q9JI76 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 56622 | ||||||||
| UniGene | Mm.117130 | ||||||||
| RefSeq | NP_065063 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Adam21 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS26022 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AF251559 AK014827 BC132152 BC132344 | ||||||||
| GenPept | AAF74731 AAI32153 AAI32345 BAB29569 | ||||||||