Version 5.4
Mus musculus Protein: Poln
Summary
InnateDB Protein IDBP-154734.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Poln
Protein Name DNA polymerase N
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000036110
InnateDB Gene IDBG-154732 (Poln)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed only in testis namely in primary spermatocytes and in round spermatids. {ECO:0000269PubMed:12794064}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005515 protein binding
GO:0030332 cyclin binding
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0006260 DNA replication
GO:0006261 DNA-dependent DNA replication
GO:0006281 DNA repair
GO:0019985 translesion synthesis
GO:0036297 interstrand cross-link repair
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:2675617
InterPro IPR001098 DNA-directed DNA polymerase, family A, palm domain
IPR002298 DNA polymerase A
IPR012337 Ribonuclease H-like domain
PFAM PF00476
PRINTS PR00868
PIRSF
SMART SM00482
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7TQ07
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 272158
UniGene
RefSeq NP_862905
MGI ID
MGI Symbol Poln
OMIM
CCDS CCDS39067
HPRD
IMGT
EMBL AK133063 AY135562
GenPept AAN39837 BAE21491

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca