Version 5.4
Mus musculus Protein: Cdkn2aip
Summary
InnateDB Protein IDBP-154746.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cdkn2aip
Protein Name CDKN2A interacting protein
Synonyms 4921511I16Rik; AW208986; CARF;
Species Mus musculus
Ensembl Protein ENSMUSP00000043713
InnateDB Gene IDBG-154744 (Cdkn2aip)
Protein Structure
UniProt Annotation
Function Activates p53/TP53 by CDKN2A-dependent and CDKN2A- independent pathways. {ECO:0000250}.
Subcellular Localization Nucleus, nucleoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0002039 p53 binding
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0009967 positive regulation of signal transduction
GO:0030308 negative regulation of cell growth
GO:0031647 regulation of protein stability
Cellular Component
GO:0001652 granular component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1918175
InterPro IPR014720 Double-stranded RNA-binding domain
IPR021859 Protein of unknown function DUF3469
PFAM PF00035
PF11952
PRINTS
PIRSF
SMART SM00358
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BI72
PhosphoSite PhosphoSite-Q8BI72
TrEMBL
UniProt Splice Variant
Entrez Gene 70925
UniGene Mm.476220
RefSeq NP_765995
MGI ID
MGI Symbol Cdkn2aip
OMIM
CCDS CCDS22299
HPRD
IMGT
EMBL AK048437
GenPept BAC33336

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca