Version 5.4
Mus musculus Protein: Smg9
Summary
InnateDB Protein IDBP-154767.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Smg9
Protein Name RIKEN cDNA 1500002O20 gene
Synonyms 1500002O20Rik; AI429693; N28092;
Species Mus musculus
Ensembl Protein ENSMUSP00000002280
InnateDB Gene IDBG-154765 (Smg9)
Protein Structure
UniProt Annotation
Function Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG8 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required for the efficient association between SMG1 and SMG8 (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID MGI:1919247
InterPro IPR019354 Smg8/Smg9
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF10220
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9DB90
PhosphoSite PhosphoSite-Q9DB90
TrEMBL D3Z719
UniProt Splice Variant
Entrez Gene 71997
UniGene Mm.150977
RefSeq NP_082323
MGI ID
MGI Symbol Smg9
OMIM
CCDS CCDS20949
HPRD
IMGT
EMBL AC159140 AK005126 AK039368 AK141576 AK161454 AK169651 BC034211
GenPept AAH34211 BAB23829 BAC30328 BAE24745 BAE36406 BAE41275

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca