InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pgap1

Summary

InnateDB Protein

IDBP-154849.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pgap1

Protein Name

post-GPI attachment to proteins 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000095346

InnateDB Gene

IDBG-154847 (Pgap1)

Protein Structure

UniProt Annotation

Function

Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi (By similarity). {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004518	nuclease activity
GO:0016788	hydrolase activity, acting on ester bonds
GO:0042578	phosphoric ester hydrolase activity

Biological Process

GO:0006505	GPI anchor metabolic process
GO:0006506	GPI anchor biosynthetic process
GO:0006886	intracellular protein transport
GO:0007605	sensory perception of sound
GO:0009880	embryonic pattern specification
GO:0009948	anterior/posterior axis specification
GO:0015798	myo-inositol transport
GO:0021871	forebrain regionalization
GO:0060322	head development
GO:0090305	nucleic acid phosphodiester bond hydrolysis