Version 5.4
Mus musculus Protein: Cadm4
Summary
InnateDB Protein IDBP-154864.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cadm4
Protein Name cell adhesion molecule 4
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000066880
InnateDB Gene IDBG-154862 (Cadm4)
Protein Structure
UniProt Annotation
Function Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity. {ECO:0000269PubMed:14659875}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in the brain and several organs including the kidney and liver. {ECO:0000269PubMed:14659875}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
Cellular Component
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:2449088
InterPro IPR003585 Neurexin/syndecan/glycophorin C
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin
IPR013162 CD80-like, immunoglobulin C2-set
PFAM PF07679
PF07686
PF00047
PF08205
PRINTS
PIRSF
SMART SM00294
SM00408
SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R464
PhosphoSite PhosphoSite-Q8R464
TrEMBL
UniProt Splice Variant
Entrez Gene 260299
UniGene Mm.178322
RefSeq NP_694752
MGI ID
MGI Symbol Cadm4
OMIM
CCDS CCDS20951
HPRD
IMGT
EMBL AY059394
GenPept AAL29692

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca