InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nsd1

Summary

InnateDB Protein

IDBP-155074.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Nsd1

Protein Name

nuclear receptor-binding SET-domain protein 1

Synonyms

AI528500; KMT3B;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000097089

InnateDB Gene

IDBG-155072 (Nsd1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	7 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0003712	transcription cofactor activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0018024	histone-lysine N-methyltransferase activity
GO:0042054	histone methyltransferase activity
GO:0050681	androgen receptor binding

Biological Process

GO:0001702	gastrulation with mouth forming second
GO:0006355	regulation of transcription, DNA-templated
GO:0016571	histone methylation
GO:0034968	histone lysine methylation
GO:0045893	positive regulation of transcription, DNA-templated

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:1276545

InterPro

IPR000313 PWWP domain
IPR001214 SET domain
IPR001841 Zinc finger, RING-type
IPR001965 Zinc finger, PHD-type
IPR003616 Post-SET domain
IPR006560 AWS
IPR011011 Zinc finger, FYVE/PHD-type
IPR019787 Zinc finger, PHD-finger

PFAM

PF00855
PF00856
PF13639
PF14634
PF00628

PRINTS

PIRSF

SMART

SM00293
SM00317
SM00184
SM00249
SM00508
SM00570

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite