InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rab24

Summary

InnateDB Protein

IDBP-155220.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rab24

Protein Name

RAB24, member RAS oncogene family

Synonyms

6530406O07Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000046188

InnateDB Gene

IDBG-155218 (Rab24)

Protein Structure

UniProt Annotation

Function

May be involved in autophagy-related processes.

Subcellular Localization

Cytoplasm, cytosol. Membrane; Lipid-anchor. Note=Only about 20% is recovered in the particulate fraction.

Disease Associations

Tissue Specificity

Widely expressed, with highest expression in brain. {ECO:0000269PubMed:8126105}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0005525	GTP binding

Biological Process

GO:0006184	GTP catabolic process
GO:0006886	intracellular protein transport
GO:0006913	nucleocytoplasmic transport
GO:0006914	autophagy
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0015031	protein transport

Cellular Component

GO:0005622	intracellular
GO:0005739	mitochondrion
GO:0005776	autophagic vacuole
GO:0005829	cytosol
GO:0016020	membrane

Protein Structure and Domains

PDB ID

MGI:105065

InterPro

IPR001806 Small GTPase superfamily
IPR002041 Ran GTPase
IPR003578 Small GTPase superfamily, Rho type
IPR003579 Small GTPase superfamily, Rab type
IPR005225 Small GTP-binding protein domain
IPR006689 Small GTPase superfamily, ARF/SAR type
IPR013684 Mitochondrial Rho-like
IPR020849 Small GTPase superfamily, Ras type
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00071
PF00025
PF08477

PRINTS

PR00449
PR00627
PR00328

PIRSF

SMART

SM00176
SM00174
SM00175
SM00173

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt