Mus musculus Protein: Pkn3
Summary
InnateDB Protein IDBP-155261.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pkn3
Protein Name protein kinase N3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000041025
InnateDB Gene IDBG-155259 (Pkn3)
Protein Structure
UniProt Annotation
Function Contributes to invasiveness in malignant prostate cancer. {ECO:0000269PubMed:15282551}.
Subcellular Localization Nucleus {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Note=Nuclear and perinuclear Golgi region. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004697 protein kinase C activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0010631 epithelial cell migration
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID MGI:2388285
InterPro IPR000008 C2 domain
IPR000719 Protein kinase domain
IPR000961 AGC-kinase, C-terminal
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR011072 HR1 rho-binding repeat
IPR017892 Protein kinase, C-terminal
IPR020635 Tyrosine-protein kinase, catalytic domain
PFAM PF00168
PF00069
PF07714
PF02185
PF00433
PRINTS PR00360
PR00109
PIRSF
SMART SM00239
SM00133
SM00220
SM00742
SM00219
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8K045
PhosphoSite PhosphoSite-Q8K045
TrEMBL
UniProt Splice Variant
Entrez Gene 263803
UniGene Mm.233843
RefSeq NP_722500
MGI ID
MGI Symbol Pkn3
OMIM
CCDS CCDS15867
HPRD
IMGT
EMBL BC034126
GenPept AAH34126