InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Zfyve1

Summary

InnateDB Protein

IDBP-155287.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Zfyve1

Protein Name

zinc finger, FYVE domain containing 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000042224

InnateDB Gene

IDBG-155285 (Zfyve1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Golgi apparatus, Golgi stack {ECO:0000250}. Endoplasmic reticulum. Note=Resides predominantly in the cisternal stacks of the Golgi. Colocalizes with TRIM13 on the perinuclear endoplasmic reticulum (By similarity). {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005545	1-phosphatidylinositol binding
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
GO:0046872	metal ion binding

Biological Process

GO:0010923

negative regulation of phosphatase activity

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005795	Golgi stack
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

MGI:3026685

InterPro

IPR000306 FYVE zinc finger
IPR009030 Insulin-like growth factor binding protein, N-terminal
IPR011011 Zinc finger, FYVE/PHD-type
IPR017455 Zinc finger, FYVE-related
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF01363

PRINTS

PIRSF

SMART

SM00064

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q810J8