InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Bnip1

Summary

InnateDB Protein

IDBP-155424.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Bnip1

Protein Name

BCL2/adenovirus E1B interacting protein 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000015725

InnateDB Gene

IDBG-155422 (Bnip1)

Protein Structure

UniProt Annotation

Function

SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death. May be involved in mitochondrial autophagy (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005484	SNAP receptor activity
GO:0005515	protein binding

Biological Process

GO:0006914	autophagy
GO:0006915	apoptotic process
GO:0007029	endoplasmic reticulum organization
GO:0015031	protein transport
GO:0016192	vesicle-mediated transport
GO:0016320	endoplasmic reticulum membrane fusion

Cellular Component

GO:0000139	Golgi membrane
GO:0005635	nuclear envelope
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral component of membrane
GO:0031201	SNARE complex
GO:0043231	intracellular membrane-bounded organelle