InnateDB Protein
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IDBP-155639.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Endog
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Protein Name
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endonuclease G
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000015481
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InnateDB Gene
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IDBG-155637 (Endog)
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Protein Structure
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Function |
Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA (By similarity). {ECO:0000250}.
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Subcellular Localization |
Mitochondrion.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
4 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1261433
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InterPro |
IPR001604
DNA/RNA non-specific endonuclease
IPR020821
Extracellular Endonuclease, subunit A
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PFAM |
PF01223
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PRINTS |
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PIRSF |
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SMART |
SM00892
SM00477
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TIGRFAMs |
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Modification |
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SwissProt |
O08600
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PhosphoSite |
PhosphoSite-O08600
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TrEMBL |
Q3UN47
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UniProt Splice Variant |
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Entrez Gene |
13804
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UniGene |
Mm.474473
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RefSeq |
NP_031957
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MGI ID |
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MGI Symbol |
Endog
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OMIM |
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CCDS |
CCDS15872
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HPRD |
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IMGT |
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EMBL |
AB012108
AK144459
BC030177
CH466542
X99394
X99395
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GenPept |
AAH30177
BAA28168
BAE25900
CAA67768
CAA67769
EDL08440
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