InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dmrtc2

Summary

InnateDB Protein

IDBP-155700.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dmrtc2

Protein Name

doublesex and mab-3 related transcription factor like family C2

Synonyms

4933432E21Rik; Dmrt7;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000011493

InnateDB Gene

IDBG-155698 (Dmrtc2)

Protein Structure

UniProt Annotation

Function

May be involved in sexual development.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00070}.

Disease Associations

Tissue Specificity

Expressed in testis. Highly expressed in ovary.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0042803	protein homodimerization activity
GO:0043565	sequence-specific DNA binding
GO:0046872	metal ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007141	male meiosis I
GO:0007290	spermatid nucleus elongation
GO:0007548	sex differentiation
GO:1900111	positive regulation of histone H3-K9 dimethylation
GO:1900114	positive regulation of histone H3-K9 trimethylation