InnateDB Protein
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IDBP-156076.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Rabac1
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Protein Name
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Rab acceptor 1 (prenylated)
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Synonyms
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2310040I06Rik; Gbpap1; PRA1; prenylin;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000076227
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InnateDB Gene
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IDBG-156074 (Rabac1)
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Protein Structure
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Function |
General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI1 (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm {ECO:0000250}. Golgi apparatus {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250}. Note=According to PubMed:11535589, it is an integral membrane protein, while other authors showed that it is cytoplasmic and membrane-associated to Golgi and synaptic vesicles. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 42 interaction(s) predicted by orthology.
Experimentally validated |
Total |
7
[view]
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Protein-Protein |
7
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
42 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1201692
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InterPro |
IPR004895
Prenylated rab acceptor PRA1
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PFAM |
PF03208
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9Z0S9
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PhosphoSite |
PhosphoSite-Q9Z0S9
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
14470
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UniGene |
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RefSeq |
NP_034391
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MGI ID |
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MGI Symbol |
Rabac1
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OMIM |
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CCDS |
CCDS20968
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HPRD |
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IMGT |
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EMBL |
AF120162
AF252856
AK008559
AK009726
AK150681
AK170289
BC008242
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GenPept |
AAD17296
AAF68476
AAH08242
BAB25744
BAB26465
BAE29761
BAE41689
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