InnateDB Protein
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IDBP-156551.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Smek2
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Protein Name
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SMEK homolog 2, suppressor of mek1 (Dictyostelium)
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Synonyms
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AW011752; AW557776; mKIAA1387;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000099920
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InnateDB Gene
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IDBG-156549 (Smek2)
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Protein Structure
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Function |
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Note=In interphase localized in the cytoplasm and (with higher levels) the nucleus. During metaphase located in pericentriolar regions.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
10 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2144474
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InterPro |
IPR006887
Domain of unknown function DUF625
IPR016024
Armadillo-type fold
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PFAM |
PF04802
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q922R5
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PhosphoSite |
PhosphoSite-Q922R5
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
104570
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UniGene |
Mm.488442
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RefSeq |
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MGI ID |
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MGI Symbol |
Smek2
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AK037253
AK041513
AK090014
AK129344
AK133211
BC006870
BX000351
BX294116
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GenPept |
AAH06870
BAC29779
BAC30967
BAC41046
BAC98154
BAE21560
CAI25082
CAI25083
CAI35921
CAI35922
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