Mus musculus Protein: Cpz
Summary
InnateDB Protein IDBP-156828.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cpz
Protein Name carboxypeptidase Z
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000039804
InnateDB Gene IDBG-156826 (Cpz)
Protein Structure
UniProt Annotation
Function Cleaves substrates with C-terminal arginine residues. Probably modulates the Wnt signaling pathway, by cleaving some undefined protein. May play a role in cleavage during prohormone processing (By similarity). {ECO:0000250}.
Subcellular Localization Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004181 metallocarboxypeptidase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0016055 Wnt signaling pathway
GO:0016485 protein processing
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:88487
InterPro IPR000834 Peptidase M14, carboxypeptidase A
IPR008969 Carboxypeptidase-like, regulatory domain
IPR020067 Frizzled domain
PFAM PF00246
PF01392
PRINTS PR00765
PIRSF
SMART SM00631
SM00063
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R4V4
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 242939
UniGene Mm.108557
RefSeq NP_694747
MGI ID
MGI Symbol Cpz
OMIM
CCDS CCDS19229
HPRD
IMGT
EMBL AC116705 AF356844 CH466524
GenPept AAM00219 EDL37485