InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pdia5

Summary

InnateDB Protein

IDBP-156873.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pdia5

Protein Name

protein disulfide isomerase associated 5

Synonyms

2700053F16Rik; AU015525; Pdir;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000023550

InnateDB Gene

IDBG-156871 (Pdia5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Endoplasmic reticulum lumen {ECO:0000255PROSITE-ProRule:PRU10138}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003756	protein disulfide isomerase activity
GO:0016209	antioxidant activity
GO:0016491	oxidoreductase activity

Biological Process

GO:0006457	protein folding
GO:0034976	response to endoplasmic reticulum stress
GO:0045454	cell redox homeostasis
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005788	endoplasmic reticulum lumen

Protein Structure and Domains

PDB ID

MGI:1919849

InterPro

IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
IPR012336 Thioredoxin-like fold
IPR013766 Thioredoxin domain

PFAM

PF00578
PF13098
PF13192
PF13462
PF13905
PF00085

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q921X9

PhosphoSite

PhosphoSite-Q921X9

TrEMBL

Q9CSM8

UniProt Splice Variant

Entrez Gene

72599

UniGene

RefSeq

NP_082571

MGI ID

MGI Symbol

Pdia5

OMIM

CCDS

CCDS37323

HPRD

IMGT

EMBL

AK012415 BC009151

GenPept

AAH09151 BAB28225