InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Atoh8

Summary

InnateDB Protein

IDBP-156896.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Atoh8

Protein Name

atonal homolog 8 (Drosophila)

Synonyms

4933425C05Rik; bHLHa21; Hath6; Math6; okadin;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000036981

InnateDB Gene

IDBG-156894 (Atoh8)

Protein Structure

UniProt Annotation

Function

Putative transcription factor. May be implicated in specification and differentiation of neuronal cell lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Expressed by subsets of mature neurons. Expressed in kidney (podocytes). {ECO:0000269PubMed:11733035, ECO:0000269PubMed:16937370}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0046983	protein dimerization activity

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007399	nervous system development
GO:0030154	cell differentiation