Version 5.4
Homo sapiens Protein: MBOAT4
Summary
InnateDB Protein IDBP-15701.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MBOAT4
Protein Name membrane bound O-acyltransferase domain containing 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000314196
InnateDB Gene IDBG-15699 (MBOAT4)
Protein Structure
UniProt Annotation
Function Mediates the octanoylation of ghrelin at 'Ser-3'. Can use a variety of fatty acids as substrates including octanoic acid, decanoic acid and tetradecanoic acid. {ECO:0000269PubMed:18443287}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed predominantly in stomach with moderate levels in pancreas and relatively low levels in most other tissues. {ECO:0000269PubMed:18443287}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0016412 serine O-acyltransferase activity
Biological Process
GO:0018191 peptidyl-serine octanoylation
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0030176 integral component of endoplasmic reticulum membrane
Protein Structure and Domains
PDB ID
InterPro IPR004299 Membrane bound O-acyl transferase, MBOAT
PFAM PF03062
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96T53
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 619373
UniGene Hs.627194
RefSeq NP_001094386
HUGO HGNC:32311
OMIM 611940
CCDS CCDS47835
HPRD
IMGT
EMBL AC026979 AF359269 EU518495
GenPept AAK43717 ACB05873

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca