InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Vamp5

Summary

InnateDB Protein

IDBP-157242.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Vamp5

Protein Name

vesicle-associated membrane protein 5

Synonyms

AF119384; Camp;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000098843

InnateDB Gene

IDBG-157240 (Vamp5)

Protein Structure

UniProt Annotation

Function

May participate in trafficking events that are associated with myogenesis, such as myoblast fusion and/or GLUT4 trafficking.

Subcellular Localization

Cell membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}. Endomembrane system {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}. Golgi apparatus, trans-Golgi network membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}. Note=Associated with the plasma membrane as well as intracellular perinuclear and peripheral vesicular structures of myotubes. Associated with the trans-Golgi, but not with the cis-Golgi apparatus.

Disease Associations

Tissue Specificity

Preferentially expressed in the skeletal muscle and heart, detected at lower levels in several other tissues but not in the brain.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000149	SNARE binding
GO:0005484	SNAP receptor activity

Biological Process

GO:0006887	exocytosis
GO:0006906	vesicle fusion
GO:0007269	neurotransmitter secretion
GO:0007519	skeletal muscle tissue development
GO:0016192	vesicle-mediated transport
GO:0030154	cell differentiation
GO:0043001	Golgi to plasma membrane protein transport

Cellular Component

GO:0005770	late endosome
GO:0005802	trans-Golgi network
GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0008021	synaptic vesicle
GO:0009986	cell surface
GO:0014704	intercalated disc
GO:0016021	integral component of membrane
GO:0030659	cytoplasmic vesicle membrane
GO:0031201	SNARE complex
GO:0031301	integral component of organelle membrane
GO:0048471	perinuclear region of cytoplasm
GO:0070062	extracellular vesicular exosome